Dr. Andrew Judge

Delitto D, Judge SM, Delitto AE, Nosacka RL, Rocha FG, DiVita BB, Gerber MH, George TJ Jr, Behrns KE, Hughes SJ, Wallet SM, Judge AR, Trevino JG. Human pancreatic cancer xenograsts recapitulate key aspects of cancer cachexia. Oncotarget. Jan 3;8(1):1177-1189, 2017

Delitto D, Judge SM, George TJ Jr, Sarosi GA, Thomas RM, Behrns KE, Hughes SJ, Judge AR, Trevino JG. A clinically applicable muscular index predicts long-term survival in resectable pancreatic cancer. Surgery. Dec 5, 2016

Ryder DJ, Judge SM, Beharry AW, Farnsworth CL, Silva JC and Judge AR. Identification of the Acetylation and Ubiquitin-Modified Proteome during the Progression of Skeletal Muscle Atrophy. PLoS ONE. Aug 24;10(8), 2015

Judge SM, Wu CL, Beharry AW, Roberts BM, Ferreira LF, Kandarian SC and Judge AR. Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia. BMC Cancer. Dec 24;14:997, 2014

Beharry AW, Sandesara PB, Roberts BM, Ferreira LF, Senf SM, and Judge AR. HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy. J Cell Sci. Apr 1;127(Pt 7):1441-53, 2014

Roberts BM, Frye GS, Ahn B, Ferreira LF and Judge AR. Cancer cachexia decreases specific Force and accelerates fatigue in limb muscle. Biochem Biophys Res Commun. Jun 7;435(3):488-92, 2013

Senf SM, Howard TM, Ahn B, Ferreira LF and Judge AR. Loss of the inducible Hsp70 delays the inflammatory response to skeletal muscle injury and severely impairs muscle regeneration. PLoS ONE. Apr 23;8(4), 2013

Roberts BM, Ahn B, Smuder AJ, Al-Rajhi M, Gill LC, Beharry AW, Powers SK, Fuller DD, Ferreira LF, Judge AR. Diaphragm and ventilatory dysfunction during cancer cachexia. The FASEB J. Jul;27(7):2600-10, 2013

Reed SA, Sandesara PB, Senf SM and Judge AR. Inhibition of FoxO transcriptional activity prevents muscle fiber atrophy during cachexia and induces hypertrophy. FASEB J. Mar; 26(3):987-1000, 2012

Senf SM, Sandesara PB, Reed SA, and Judge AR. Acetyltransferase Activity Differentially Regulates the Localization and Activity of the FOXO Homologues in Skeletal Muscle.  Am J. Physiol. Cell Physiol. Jun;300(6):C1490-501, 2011

Reed SA, Senf SM, Cornwell EW, Kandarian SC, Judge AR. Inhibition of IkappaB kinase alpha (IKKα) or IKKbeta (IKKβ) plus forkhead box O (Foxo) abolishes skeletal muscle atrophy. Biochem Biophys Res Commun. Feb 18;405(3):491-6, 2011

Senf SM, Dodd SL and Judge AR. FOXO Signaling is Required for Disuse Muscle Atrophy and is Directly Regulated by Hsp70. Am J. Physiol. Cell Physiol. Jan;298(1):C38-45, 2010

Dodd SL, Hain BA, Senf SM and Judge AR. Hsp27 inhibits IKKb-induced NF-kB activity and skeletal muscle atrophy. FASEB J. Oct;23(10):3415-23, 2009

Senf SM, Dodd SL, McClung JM, Judge AR. Hsp70 overexpression inhibits NF-kB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy. FASEB J. Nov;22(11):3836-45, 2008