BREATHE Research understanding & treating neuromuscular disorders that compromise respiratory and non-respiratory function

With active members in 17 departments and interests in preclinical, clinical, and translational research, the UF BREATHE Center Research Cores provide a nexus for interdisciplinary collaborations.

Research Cores

Basic Breathing Research Core

Fundamental principles in the neural control of breathing and respiratory muscles are explored. Major areas of strength include: respiratory motor plasticity, opioid induced respiratory depression and muscle wasting with neuromuscular injury/disease, aging, heart failure, sepsis and cancer.


Neurological Disorders Core

Major strengths include respiratory function in neuromuscular disorders (Spinal Cord Injury, Pompe Disease, Duchenne Muscular Dystrophy and ALS), neurodegenerative diseases (Parkinson’s disease, Alzheimer’s disease), and other clinical disorders (cancer cachexia, heart failure, sleep apnea).

neurological disorders

Spinal Cord Injury Core

The UF BREATHE Center is devoted to developing new therapeutics to restore breathing and airway defense, walking, and health in those living with spinal cord injuries. A particular focus is to harness spinal cord plasticity through intermittent hypoxia or spinal cord electrical stimulation to restore function.

spinal cord

Recruiting Patients

Current Clinical Trials

BREATHE members run a variety of clinical trials focused on respiratory research and rehabilitation.

IH trial